Molecular mechanisms of oxidative stress in aging: free radicals, aging, antioxidants and disease
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منابع مشابه
Oxidative Stress and Human Disease: a Review
Background: The human body needs both types of oxidants (free radicals) and antioxidants for normal metabolism, signal transduction mechanism, and the order of cellular activity. Free radicals can be either harmful or helpful to the body, in fact, they play a dual role as both toxic and beneficial compounds. The human body has the natural antioxidant defense mechanism to counteract the free rad...
متن کاملStudies on free radicals, antioxidants, and co-factors
The interplay between free radicals, antioxidants, and co-factors is important in maintaining health, aging and age-related diseases. Free radicals induce oxidative stress, which is balanced by the body's endogenous antioxidant systems with an input from co-factors, and by the ingestion of exogenous antioxidants. If the generation of free radicals exceeds the protective effects of antioxidants,...
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Parkinson's disease (PD), a neurodegenerative movement disorder of the central nervous system (CNS) is characterized by a progressive loss of dopaminergic neurons in the substantia nigra pars compacta region of the midbrain. Although the etiology of PD is not completely understood and is believed to be multifactorial, oxidative stress and mitochondrial dysfunction are widely considered major co...
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Background: Reishi (Ganoderma lucidum) is a mushroom that has been used in Asian countries for thousands of years as a culinary-medicinal mushroom to treat a variety of diseases. Objective: To evalzuate the studies conducted on anti-aging effects of Reishi mushroom. Methods: Scopus, PubMed, Google Scholar, SID, and MagIran databases were used to search for articles published during 1989-2023...
متن کاملFree Radicals, Antioxidants in Disease and Health
Free radicals and oxidants play a dual role as both toxic and beneficial compounds, since they can be either harmful or helpful to the body. They are produced either from normal cell metabolisms in situ or from external sources (pollution, cigarette smoke, radiation, medication). When an overload of free radicals cannot gradually be destroyed, their accumulation in the body generates a phenomen...
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تاریخ انتشار 1999